A 83-01 _ 53002ESA 83 01 is a potent inhibitor of TGF type I receptor ALK5 (IC50: 12 nM) ALK4 ((IC50: 45 nM) ALK7 (IC50: 7. 5 nM) kinase, A 83 01 has a strong inhibitory effect on ALK5 and can inhibit phosphorylation of Smad2 3 and TGF induced growth. A 83 01 has little or no effect on bone morphogenetic protein type I receptors, p38 mitogen activated protein kinases, or extracellular regulatory kinases. At the same time, A 83 01 inhibits TGF induced epithelial

Human GCP-2/CXCL6

EGFR is overexpressed in a wide variety of tumors and is the target of several anti-cancer drugs

Measured in a cell proliferation assay using human peripheral blood monocytes

It is essential for proper development of lymph node germinal centers and Peyer's patches

Recombinant Human Calprotectin (S100A8&S100A9) Protein is expressed from E

Avoid cross contamination and aerosol contamination

25~16 ng/mL

[Accession | P46531]

Glycerol-free (5U/μL)

Standard curve range: 30 fg/μL – 300 pg/μL

Perform the reaction at 25℃ for 1 h (hot lid off)

20mM Hepes-KOH